6-Formylindolo(3,2-b)carbazole, CAS 172922-91-7

Ah receptor ligand

Product Type: Ligand

CAS No.: 172922-91-7

MolecularFormula: C19H12N2O

Molecular Weight: 284,3

Source: Synthetic

Purity: >95%

Solubility: Soluble in DMSO (10 mg/ml)

Appearance: Yellow solid

PubChem CID: 22245026

Scientific Background: A tryptophan-derived, high affinity aryl hydrocarbon receptor ligand (Kd=7x10-11 M). Proposed to be an endogenous AhR ligand. Induces rapid and transient expression of cytochrome P450-1A1 (CYP1A1) in human cells at 100 pM.

References: 1. Wei Y.D., et al. (1998) Chem. Biol. Interact. 110(1-2): 39-55. 2. Rannug U., et al. (1995) Chem. Biol. Drug. Des. 2(12): 841-855.3. Rannug A., et al. (1987) J. Biol. Chem. 262(32): 15422-7.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-383-100UG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-383-100UG
• Package Unit: 100 µg
• Quantity Unit: STK