7-Benzyloxy-4-(trifluoromethyl)coumarin, CAS 220001-53-6

Formulation: A solid

Formal Name: 7-(phenylmethoxy)-4-(trifluoromethyl)-2H-1-benzopyran-2-one

Purity: ≥95%

Formula Markup: C17H11F3O3

Formula Weight: 320,3

Shelf life (days): 1460

CAS Number: 220001-53-6

Notes: 7-Benzyloxy-4-(trifluoromethyl)coumarin (BFC) is a fluorogenic substrate for the cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A.{64597,64598} Upon enzymatic cleavage by CYP1A2 or CYP3A, 7-hydroxy-4-(trifluoromethyl)coumarin (HFC) is released and its fluorescence can be used to quantify CYP1A2 and CYP3A activity. HFC displays excitation/emission maxima of 410/510 nm, respectively.

• SKU: CAY35721-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 35721-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK
• Application: Reinstoffe, Fluorescence