Formulation: A solid
Formal Name: 8-amino-7-oxo-nonanoic acid, monohydrochloride
Purity: ≥95%
Formula Markup: C9H17NO3 • HCl
Formula Weight: 223,7
Shelf life (days): 730
CAS Number: 21286-96-4
Notes: (±)8-Amino-7-Oxononanoic acid ((±)8-KAPA) is a racemic mixture of 8(R)-KAPA and the vitamer of biotin 8(S)-KAPA (Item No. 10007542).{64206,66719} It is biosynthesized as the 8(S) form but racemizes in culture media in a pH-dependent manner, with a higher racemization rate under very low (pH S. cerevisiae in a concentration-dependent manner and is an intermediate in the biosynthesis of biotin (Item No. 22582) in microbes. 8(S)-KAPA, but not 8(R)-KAPA, is a substrate for E. coli and M. tuberculosis 7,8-diaminopelargonic acid aminotransferase (DAPA AT), which leads to accumulation of 8(R)-KAPA in M. tuberculosis cultures after exogenous application of racemic KAPA.
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