Formulation: A solution in ethanol
Formal Name: (5Z)-7-[(2S,3R)-3-(2Z,5Z)-2,5-undecadien-1-yl-2-oxiranyl]-5-heptenoic acid
Purity: ≥95%
Formula Markup: C20H32O3
Formula Weight: 320,5
Shelf life (days): 365
CAS Number: 123931-39-5
Notes: 8S(9R)-EET is an oxylipin and a metabolite of arachidonic acid (Item Nos. 90010 / 90010.1 / 10006607).{313} It is formed via oxidation of arachidonic acid by the cytochrome P450 (CYP) isoforms CYP1A1, CYP1A2, CYP2B1, and CYP2B2. 8S(9R)-EET induces relaxation of precontracted isolated dog epicardial arterioles (EC50 = 121 pM).{52399} Intrarenal infusion of 8S(9R)-EET (0.5, 1, or 2 µg/kg per minute) induces glomerular vasoconstriction and reduces the glomerular filtration rate in rats.{1111}