Formulation: A crystalline solid
Formal Name: N1,N16-didodecyl-4,7,13-tris[3-(dodecylamino)-3-oxopropyl]-4,7,10,13-tetraazahexadecanediamide
Purity: ≥95%
Formula Markup: C81H163N9O5
Formula Weight: 1343,2
Shelf life (days): 730
CAS Number: 917572-74-8
Notes: 98N12-5 is an ionizable cationic lipid.{69238} It has been used in combination with other lipids in the generation of lipid nanoparticles (LNPs). LNPs containing 98N12-5 and encapsulating proprotein convertase subtilisin kexin type 9 (PCSK9) siRNA selectively accumulate in the liver and reduce total serum cholesterol levels in mice and rats and serum LDL levels in cynomolgus monkeys.{69239}