α-Conotoxin Im-I, CAS 156467-85-5

α-Conotoxin Im-I, CAS 156467-85-5
SKU
MEXHY-P1270-1
Packaging Unit
1 mg
Manufacturer
MedChemExpress

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Product Description: α-Conotoxin Im-I is a selective α7/α9 nAChR antagonist, blocking α7 nicotinic receptors with the highest apparent affinity, while having an 8-fold lower affinity for homomeric α9 nicotinic receptors. α-Conotoxin Im-I is toxic and induces seizures in rodents. α-Conotoxin Im-I is a tool for studying neuronal nAChR[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C52H78N20O15S4

References: [1]Johnson DS, et al. alpha-Conotoxin ImI exhibits subtype-specific nicotinic acetylcholine receptor blockade: preferential inhibition of homomeric alpha 7 and alpha 9 receptors. /[2]Quiram P A, et al. Pairwise interactions between neuronal α7acetylcholine receptors and α-conotoxin PnIB. Journal of Biological Chemistry, 2000, 275(7): 4889-4896.

CAS Number: 156467-85-5

Molecular Weight: 1351.56

Compound Purity: 98.15

Research Area: Neurological Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: nAChR
More Information
SKU MEXHY-P1270-1
Manufacturer MedChemExpress
Manufacturer SKU HY-P1270-1
Green Labware No
Package Unit 1 mg
Quantity Unit STK
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