Products from BPS Bioscience require a minimum order value above 400€
Applications: Useful for studying enzyme kinetics and screening small molecule inhibitors and antibodies for drug discovery and HTS applications.
Background: Angiotensin converting enzyme 2 (ACE2) is an exopeptidase that catalyzes the conversion of angiotensin II to angiotensin 1-7 and L-phenylalanine. Angiotensin II is part of the classical renin angiotensin system (RAS), a hormone system that regulates fluid balance, blood pressure and maintains vascular tone. ACE2 has been also proved to be the receptor for the human respiratory coronavirus NL63, the SARS-coronavirus (SARS-CoV) and the novel coronavirus 2019-nCoV/SARS-CoV-2.
Description: The ACE2 Inhibitor Screening Assay Kit is designed to measure the exopeptidase activity of ACE2 for screening and profiling applications.
Storage Stability: Up to 6 months from date of receipt, when stored as recommended.
Supplied As: The ACE2 assay kit comes in a convenient 96-well format, with purified ACE2, its substrate, and ACE2 buffer for 96 reactions.
Biosafety Level: Not applicable (BSL-1)
References: Danilczyk, U., et al. Circulation Research. 2006. 98(4): 463-471.
Ge, X. Y., et al. Nature. 2013. 503(7477): 535-538.
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