Actinomycin D, CAS 50-76-0

Transcription inhibitor

Product Type: Inhibitor

CAS No.: 50-76-0

MolecularFormula: C62H86N12O16

Molecular Weight: 1255,43

Source: Synthetic

Purity: >98%

Solubility: Soluble to 50 mM in DMSO

Appearance: White Solid

PubChem CID: 2019

Scientific Background: The actinomycins are a class of polypeptide antibiotics. Actinomycin D inhibits transcription by binding DNA at the transcription initiation complex and preventing elongation by RNA polymerase (1). Actinomycin D has been used as a chemotherapy drug (2), and an antibiotic.

References: 1. Sobell H. (1985) Proc Natl Acad Sci USA. 82(16): 5328-31.2. Turan T., et al. (2006) Int J Gynecol Cancer. 16(3): 1432-1438.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-245-50MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-245-50MG
• Package Unit: 50 mg
• Quantity Unit: STK