Gamma Synuclein Pre-formed Fibrils (Type 1)

Human Recombinant Gamma Synuclein Protein Pre-formed Fibrils (Type 1)

Target: Gamma Synuclein.

Nature: Recombinant.

Swiss-Prot: O76070.

Expression System: E. coli.

Protein Length: Full length.

Purification: Ion-exchange Purified.

Purity: >95%.

Storage Buffer: PBS pH 7.4.

Protein Size: 13.33 kDa.

Conjugate: No tag.

Cellular Localization: Cytoskeleton, Centrosome, Spindle, Perinuclear Region.

Scientific Background: Gamma synuclein is a neuronal protein found in peripheral and motor nerve systems. It has been implicated in the hippocampal axon pathology in Parkinson's Disease (1). A change in the expression of gamma synuclein has been observed in the retina of patients with Alzheimer's disease (2). Its expression in breast tumors is also a marker for tumor progression (3).

References: 1. Nishioka K., et al. (2010) Arch Neurol. 67(8): 970-975. 2. Surgucheva I., Newell K.L., Burns J., Surguchov A. (2014) Acta Neuropathol Commun. 2: 132. 3. Bruening. W., et al. (2000) Cancer. 88(9): 2154-2163. 4. Mukaetova-Ladinska E.B., et al. (2008) Dement Geriatr Cogn Disord. 26(1): 32-42.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For research use only.

• SKU: STRSPR-459B
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SPR-459B
• Green Labware: No
• Package Unit: 100 µg
• Quantity Unit: STK
• Reactivity: Human
• Application: Western Blotting, In Vivo Assay, SDS-PAGE
• Human Gene ID: 6623