Abbreviation: ACVRL1
Target Synonym: ACVRL1;ACVRLK1;ALK-1;ALK1;HHT;HHT2;ORW2;SKR3;TSR-I
Conjugation: Unconjugated
UNIProt ID: P37023
Background: This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human ACVRL1
Dilution: WB 1:500-1:2000
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