Swissprot: O95450.
Concentration: 1.32 mg/mL.
Immunogen: Synthetic peptide of human ADAMTS2.
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4.
Purification Method: Antigen affinity purification.
Conjugation: Unconjugated.
Background: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I, type II and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants.
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