ADS032, CAS 2757333-37-0

Product Description: ADS032 is a sulfonylurea compound that is an NLRP1 and NLRP3 inflammasome inhibitor. ADS032 reduces the secretion of inflammatory factors and inhibits the oligomerization of ASC. ADS032 has anti-inflammatory effects in a variety of inflammatory models and can be used in the study of inflammatory diseases[1].

Applications: COVID-19-immunoregulation

Formula: C22H29NO4S

References: [1]Docherty CA, et al. A novel dual NLRP1 and NLRP3 inflammasome inhibitor for the treatment of inflammatory diseases. Clin Transl Immunology. 2023 Jun 22;12(6):e1455.

CAS Number: 2757333-37-0

Molecular Weight: 403.53

Compound Purity: 99.74

Research Area: Inflammation/Immunology

Solubility: DMSO : 100 mg/mL (ultrasonic)/Ethanol : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Interleukin Related;NOD-like Receptor (NLR)

• SKU: MEXHY-156798-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-156798-10.1
• Package Unit: 10mM/1mL
• Quantity Unit: STK