AG 494, CAS 133550-35-3

EGFR kinase inhibitor

Product Type: Inhibitor

CAS No.: 133550-35-3

MolecularFormula: C16H12N2O3

Molecular Weight: 280,3

Source: Synthetic

Purity: ≥98% (TLC)

Solubility: Soluble in DMSO (25 mg/ml) or 100% ethanol (25 mg/ml)

Appearance: Yellow solid

PubChem CID: 5328771

Scientific Background: AG 494 is a potent inhibitor of epidermal growth factor receptor (EGFR) kinase. It specifically inhibits EGF receptor autophosphorylation and EGF-dependent cell growth.

References: 1. Ben-Bassat H., et al. (1999).J. Pharm. Exp. Ther. 290(3): 1442–1457.2. Kleinberger-Doron N., Shelah N., Capone R., Gazit A., & Levitzki A. (1998) Exp. Cell . Res. 241(2): 340–351.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-491-50MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-491-50MG
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK