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Encompassing Amino Acids: full length
Applications: Useful for ATPase activity assay for Hsp90alpha.
Background: Co-chaperone that stimulates HSP90 ATPase activity (By similarity). May affect a step in the endoplasmic reticulum to Golgi trafficking.
Description: Human recombinant full-length AHA1 with C-terminal His-tag (GenBank Accession No. NM_012111), expressed in E. coli. MW=38 kDa.
Format: Aqueous buffer solution
Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, 20% glycerol, and 200 mM imidazole
Genbank: NM_012111
Storage Stability: At least 6 months at -80°C.
Tags: C-terminal His-tag
Uniprot: O95433
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Wang, X. et al., Cell 127 (4), 803-815 (2006).
2. Lotz, G.P. et al., J. Biol. Chem. 278 (19), 17228-17235 (2003).
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