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Encompassing Amino Acids: 136-553
Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Description: Human ALAS2 (aminolevulinate, delta-, synthase 2) (GenBank Accession No. NM_000032), (a.a. 136-553) with N-terminal His-tag, MW = 46 kDa, expressed in an E. coli expression system.
Format: Aqueous buffer solution
Formulation: 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 20% glycerol, 3 mM DTT, 20 µM pyridoxal 5? phosphate monohydrate.
Genbank: NM_000032
Storage Stability: At least 6 months at -80°C.
Tags: N-terminal His-tag
Uniprot: P22557
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Lee, P.L. et al., Blood Cells Mol. Dis. 36 (2), 292-297 (2006).
2. Astner, I. et al., EMBO J. 24 (18), 3166-3177 (2005).