Clone Name: αsm-1
Application Note: IHC-P: 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 42
Specificity/Sensitivity: Reactive with smooth muscle cells in blood vessel walls, gut wall, myometrium and arrectores pili of skin. Myoepithelial cells such as those in breast and salivary gland also contain actin.
Form: Liquid
Buffer (with preservative): PBS pH7.6, 1% BSA, 0.09% Sodium azide.
Concentration: >4.5 μg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, and Moyamoya disease, as well as multisystemic smooth muscle dysfunction syndrome. [provided by RefSeq, Sep 2017]
Uniprot ID: P62736
Antigen Species: Human
Immunogen: Synthetic amino terminal decapeptide of alpha smooth muscle isoform of actin.
Purification: IgG fraction
Conjugation: Unconjugated
Full Name: actin alpha 2, smooth muscle
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