alpha Synuclein antibody (KM51)

Clone Name: KM51

Light Chain: Kappa

Application Note: IHC-P: 1:20–1:40. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 14

Specificity/Sensitivity: Does not cross react with beta-synuclein.

Form: Liquid

Buffer (with preservative): Tissue culture supernatant, 0.09% Sodium azide.

Concentration:

Background: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]

Uniprot ID: P37840

Antigen Species: Human

Immunogen: Prokaryotic recombinant protein corresponding to the majority of the full length alpha-synuclein molecule.

Purification: Unpurified

Conjugation: Unconjugated

Full Name: synuclein alpha

• SKU: GTX01946-500
• Manufacturer: GeneTex
• Manufacturer SKU: GTX01946-500
• Green Labware: No
• Package Unit: 500 μl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunohistochemistry (paraffin)
• Isotype: IgG1
• Human Gene ID: 6622
• Host: Mouse