Amifostine, CAS 20537-88-6

HIF-1α activator

Product Type: Activator

CAS No.: 20537-88-6

MolecularFormula: C5H15N2O3PS

Molecular Weight: 214,22

Source: Synthetic

Purity: >98%

Solubility: Soluble in water

Appearance: White Solid

PubChem CID: 2141

Scientific Background: Amifostine is a cytoprotective adjuvant used in cancer chemotherapy and radiotherapy. Inside cells it detoxifies reactive metabolites of platinum and alkylating agents (1, 2). Other effects include accelerated DNA repair (1), induction of cellular hypoxia (1), inhibition of apoptosis (2), alteration of gene expression (2) and modification of enzyme activity (2).

References: 1. Kouvaris J.R., Kouloulias V.E., Blahos L.J. (2007) Oncologist. 12(6): 738-747.2. Amifostine: BC Cancer Agency. 2006-03-01.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-210-50MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-210-50MG
• Package Unit: 50 mg
• Quantity Unit: STK