Product Description: Amino-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Amino-PEG4-CH2COOH is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
Applications: Cancer-programmed cell death
Formula: C10H21NO6
References: [1]Nan JI, et al. Mertk degraders and uses thereof. WO2020010210A1./[2]Maggie Lu, et al. Linker-drug and antibody-drug conjugate (adc) employing the same. EP3335734A1.