Annexin A1 / (Hairy Cell Leukemia Marker)(ANXA1/3566), 1mg/mL

Annexin A1 / (Hairy Cell Leukemia Marker)(ANXA1/3566), 1mg/mL
SKU
BTMBNUM3566-50
Packaging Unit
50 uL
Manufacturer
Biotium

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Description: Annexin A1 belongs to the annexin family. It plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. In resting conditions Annexin A1 is localized to the cytoplasm. Upon activation it is mobilized to the membrane and secreted. Annexin A1 and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. Expression of the ANXA1 gene is upregulated in hairy cell leukemia (HCL). Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: ANXA1/3566

Entrez Gene ID: 301

Immunogen: Recombinant full-length human Annexin A1 protein

Verified AB Applications: Flow (intracellular) (verified)/IF (verified)/IHC (FFPE) (verified)/WB (verified)

Z-Antibody Applications: Flow, intracellular (verified)/IF (verified)/IHC, FFPE (verified)/WB (verified)
More Information
SKU BTMBNUM3566-50
Manufacturer Biotium
Manufacturer SKU BNUM3566-50
Package Unit 50 uL
Quantity Unit STK
Reactivity Human
Clonality Monoclonal
Application Immunofluorescence, Western Blotting, Flow Cytometry, Immunohistochemistry
Isotype IgG2a kappa
Host Mouse
Conjugate Unconjugated
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