Application Note: WB: 0.1-0.5μg/ml. ICC/IF: 0.5-1μg/ml. IHC-P: 0.5-1μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Form: Liquid
Buffer (with preservative): 0.2mg Na₂HPO₄, 0.9mg NaCl, 5mg BSA, 0.05mg sodium azide, 0.05mg Thimerosal.
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The Annexin 5 gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. Polymorphisms in this gene have been implicated in various obstetric complications. [provided by RefSeq, Dec 2019]
Uniprot ID: P08758
Antigen Species: Human
Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Annexin V (88-102aa SRLYDAYELKHALKG), identical to the related rat and mouse sequences.
Purification: Purified IgG
Conjugation: Unconjugated
Full Name: annexin A5
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