Anti-Botulinum neurotoxin type A (CR1)

Anti-Botulinum neurotoxin type A [CR1], Monoclonal, IgG2, kappa, Host: Guinea Pig

CloneID: CR1

Antigen Long Description: CR1 was produced by a yeast gene diversity library used to increase the affinitiy of scFv AR2 for BoNT/A2, while maintinaing high affinity binding to BoNT/A2. AR2 was generated after multiple rounds of affinity maturation of the humanized C25, which itself was created by CDR-grafting from the parental murine C25. Murine C25 was prepared by constructing a scFv phage display library from mice immunized with recombinant BoNT/A binding domain (Hc).

Buffer Composition: PBS only.

Concentration: 1 mg/ml

Chimeric Use Statement: This chimeric guinea pig antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Uniprot Accession No.: P10845

• SKU: ABAAb00803-206.1-BT
• Manufacturer: Absolute Antibody
• Manufacturer SKU: Ab00803-206.1-BT
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK
• Reactivity: Various species
• Clonality: Monoclonal
• Application: Flow Cytometry, Neutralization
• Isotype: IgG2
• Host: Other