CloneID: cet.Hum (Cetuximab - humanized; hC225)
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was generated by grafting CDR loops of cetuximab on framework regions derived from type 3 (VH3 and VL3 kappa) human germline sequences to obtain recombinant VH and VL domains linked together with a flexible linker [(Gly4Ser)3] to form a scFv.
Origin Pub PMID: 29185855
Buffer Composition: PBS with 0.02% Proclin 300.
Concentration: 1 mg/ml
Chimeric Use Statement: This full-length reformatted human antibody was made using the variable domain sequences of the original Human scFv format for improved compatibility with existing reagents assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P00533
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