Target: iNKT cell.
Clone: 6B11.
Specificity: Anti-iNKT cell In Vivo Antibody - Low Endotoxin (6B11) recognizes an epitope on TCR V alpha 24-J alpha 18.
Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution: Invariant NKT cells.
Background: Encoded by the TCR V alpha 24-J alpha 18 germline configuration, V alpha 24-J alpha Q is expressed on a subset of NKT cells, namely invariant NKT (iNKT). V alpha 24-J alpha Q TCR interacts with the glycolipid loaded MHC class 1b molecule CD1d, inducing activation and subsequent cytokine production.
Immunogen: Unknown.
Concentration: 1.0 - 5.0 mg/ml.
Formulation: 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Purity: >95% by SDS-PAGE and HPLC.
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method.
Aggregation: Aggregation level ≤ 5%.
Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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