Target: CD120a.
Clone: 55R-170.
Specificity: Anti-CD120a In Vivo Antibody - Low Endotoxin (55R-170) recognizes an epitope on Mouse TNF RI.
Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background: Tumor necrosis factor receptor superfamily, member 1A, (TNFRI) also known as TNFRSF1A or CD120A is the principal receptor through which many of the pro-inflammatory activities of TNF-alpha are mediated. TNFRI contains a death domain through which it interacts with other death-domain proteins to promote cellular responses. It regulates immune and inflammatory responses.
Immunogen: Recombinant Mouse TNF RI Extracellular Domain.
Concentration: 1.0 mg/ml.
Formulation: 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Purity: >95% by SDS-PAGE and HPLC.
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method.
Aggregation: Aggregation level ≤ 5%.
Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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