Target: CD200.
Clone: OX-90.
Specificity: Clone OX-90 reacts with murine CD200 (OX-2).
Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution: Thymocytes, neurons, B cells, splenic follicular dendritic cells and endothelium, and subsets of T cells and dendritic cells.
Background: CD200 (OX-2) is an immune suppressor that regulates the of induction of cytokine production by conventional allostimulatory DC. CD200 limits pro-inflammatory signals and has been shown to play an important role in cancer and immune disorders.
Concentration: ≥ 2.0 mg/ml.
Formulation: Sterile, preservative-free, solution in PBS. BSA and Azide free.
Purity: >98% by SDS-PAGE and HPLC.
Endotoxin: ≤ 0.5 EU/mg as determined by the LAL method.
Aggregation: Aggregation level ≤ 1%.
Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.