CloneID: NC6.8
Heavy Chain modification: Fc Silent™
Antigen Long Description: This antibody was raised by immunizing a mouse with NC-174.
Buffer Composition: PBS only.
Chimeric Use Statement: This is a reformatted mouse IgG2b Fc Silent™ antibody, based on the original mouse IgG2b format, created for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody is specific for SC45647.
Application Notes (Clone): The structure of the original antibody was determined using x-ray crystallography (Gokulan et al., 2005; PMID:16026161, Guddat et al,. 1994; PMID:7893280). The antibody was used for a radioimmunoassay on N-(p-cyanophenyl)-N'-(diphenylmethyl) guanidineacetic acid to determine the pH sensitivity of antibody binding (Viswanathan et al., 1995; PMID:8519975).