Anti-Rat CD4, PE-Cy7 (Clone W3/25) (mouse IgG1)

Cedarlane’s anti-rat T helper cell monoclonal antibodies recognize a determinant on the majority of thymocytes (90-95%), a subset of peripheral T cells and peritoneal macrophages (1,2,3,10). The antigen recognized by this clone is a surface glycoprotein of Mr 48 000 - 52 000 and is the homologue of the human CD4 and the mouse L3/T4 antigen. Clone W3/25 labels the rat T helper subset, which mediates the helper activity for B and T cells, graft vs. host (GVH) reactivity and produces IL-2 in the mixed lymphocyte reaction (MLR) (2,4,6). Addition of W3/25 to the MLR, inhibited proliferation and blocks the production of IL-2 (4,5,6,9).

• SKU: CEDCL003PE-CY7
• Manufacturer: Cedarlane
• Manufacturer SKU: CL003PE-CY7
• Package Unit: 100 µg
• Quantity Unit: STK
• Reactivity: Rat (Rattus)
• Isotype: IgG1
• Host: Mouse
• Conjugate: Conjugated, PE-Cy7