Product Type: Inhibitor
CAS No.: 520-36-5
MolecularFormula: C15H10O5
Molecular Weight: 270,2
Source: Synthetic
Purity: >98%
Solubility: Soluble to 50 mM in DMSO
Appearance: White Solid
PubChem CID: 5280443
Scientific Background: Apigenin induces a process called autophagia (1). It is a potent inhibitor of CYP2C9, an enzyme responsible for the metabolism of many pharmaceutical drugs in the body (2). Apigenin has also been shown to reverse the adverse effects of cyclosporine (3).
References: 1. Ruela-de-Sousa R.R., et al. (2010) Cell Death and Disease. 1(e19): 1-11.2. Dayong S.I., et al. (2009) Drug Metabolism and Disposition. 37(3): 629-634.3. Chakravarthi S., Wen C.F., Nagaraja H.S. (2009) J Anal Bio Sci. 32(4): 320-327.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
English
Deutsch
