AR A014418, CAS 487021-52-3

GSK-3 kinase inhibitor

Product Type: Inhibitor

CAS No.: 487021-52-3

MolecularFormula: C12H12N4O4S

Molecular Weight: 308,3

Source: Synthetic

Purity: ≥95% (HPLC)

Solubility: Soluble in DMSO, methanol, 100% ethanol or ethyl acetate

Appearance: White to off-white solid

PubChem CID: 448014

Scientific Background: AR A014418 is a highly selective glycogen synthase kinase 3 (GSK-3) inhibitor. GSK-3 is a serine/threonine kinase that has been implicated in pathological conditions such as diabetes and Alzheimer′s disease. AR A014418 is cell permeable.

References: 1. Bhat R.V., & Budd S.L. (2002) Neuro-Signals. 11(5): 251–261. 2. Gould T.D., Einat H., Bhat R., & Manji H.K. (2004) Int. J. Neuropsychopharmacology (CINP). 7(4): 387–390.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-492-5MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-492-5MG
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK