ARN25062, CAS 3036492-85-7

Formulation: A solid

Formal Name: 6-phenyl-2-(4-piperidinyl)-N-[3-(trifluoromethyl)phenyl]-4-pyrimidinamine

Purity: ≥95%

Formula Markup: C22H21F3N4

Formula Weight: 398,4

Shelf life (days): 730

CAS Number: 3036492-85-7

Notes: ARN25062 is a derivative of ARN22089, an inhibitor of the protein-protein interaction between Cdc42 and p21-activated kinase (PAK).{51806} It inhibits the proliferation of SKM28, SK-MEL-3, WM3248, and A375 melanoma cells (IC50s = 6.1, 4.6, 9.3, and 5.1 µM, respectively) and SW480 colon cancer cells (IC50 = 5.9 µM). ARN25062 (10 mg/kg) reduces tumor growth in a patient-derived xenograft (PDX) mouse model.

• SKU: CAY39615-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 39615-5
• Package Unit: 5 mg
• Quantity Unit: STK