Formulation: A neat liquid
Formal Name: 2,3,5,6-tetrakis(2-hexyldecanoate) L-ascorbic acid
Purity: ≥95%
Formula Markup: C70H128O10
Formula Weight: 1129,8
Shelf life (days): 730
CAS Number: 183476-82-6
Notes: Ascorbyl tetraisopalmitate is a lipophilic derivative of vitamin C (L-ascorbic acid; Item No. 14656).{64552,64553} It protects against UVB-, hydrogen peroxide-, or tert-butyl hydroperoxide-induced decreases in cell viability in HaCaT keratinocytes when used at a concentration of 100 µM.{64552} Ascorbyl tetraisopalmitate (20 µM) decreases IL-1α and prostaglandin E2 (PGE2; Item No. 14010) production in unstimulated and UVB-stimulated HaCaT keratinocytes. Topical application of ascorbyl tetraisopalmitate (1%) increases viable epidermis thickness, stratum corneum water content, and skin smoothness and decreases skin roughness in hairless mice.{64553} Formulations containing ascorbyl tetraisopalmitate have been used in cosmetic products as skin-lightening agents.
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