Clone Name: ARC62108
Application Note: WB: 1:1000-1:3000. IHC-P: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 70
Form: Liquid
Buffer (with preservative): PBS pH 7.3, 0.05% BSA, 50% glycerol, 0.05% proclin300.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010]
Uniprot ID: P17405
Antigen Species: Human
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 70-340 of human SMPD1(NP_000534.3).
Purification: Purified by affinity chromatography
Conjugation: Unconjugated
Full Name: sphingomyelin phosphodiesterase 1
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