ATF5 Antibody - middle region : HRP

Conjugation: HRP: Horseradish Peroxidase

Description of Target: ATF5 belongs to the bZIP family. It is transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4. Loss of ATF5 is associated with hepatocellular carcinoma.

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ATF5

Key Reference: Zhou,D., (2008) J. Biol. Chem. 283 (11), 7064-7073

Molecular Weight: 31kDa

Peptide Sequence: Synthetic peptide located within the following region: LPPPQQPPPPSPPQPSRLAPYPHPATTRGDRKQKKRDQNKSAALRYRQRK

Product Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Protein Name: Cyclic AMP-dependent transcription factor ATF-5

Protein Size: 282

Purification: Affinity Purified

• SKU: AVIARP57977_P050-HRP
• Manufacturer: Aviva Systems Biology
• Manufacturer SKU: ARP57977_P050-HRP
• Green Labware: No
• Package Unit: 100μl
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine), Rat (Rattus), Dog (Canine), Guinea Pig, Cow (Bovine), Zebrafish, Horse (Equine)
• Clonality: Polyclonal
• Application: Western Blotting
• Human Gene ID: 22809
• Host: Rabbit