Abbreviation: ATG4B
Target Synonym: ATG4B; APG4B; AUTL1; cysteine protease ATG4B
Conjugation: Unconjugated
UNIProt ID: Q9Y4P1
Background: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human ATG4B
Dilution: WB 1:500-1:2000
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