Formulation: A solution in chloroform
Formal Name: 4,4′-[[[[3-(dimethylamino)propyl]thio]carbonyl]imino]bis-butanoic acid, 1,1′-bis(1-heptyloctyl) ester
Purity: ≥98%
Formula Markup: C44H86N2O5S
Formula Weight: 755,2
Shelf life (days): 730
CAS Number: 2230647-37-5
Notes: ATX-100 is an ionizable cationic lipid (pKa = 6.38).{64704,64703} It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA. Intravenous administration of LNPs containing ATX-100 and encapsulating Factor VII siRNA decrease Factor VII blood levels in mice.{64703}