AWL-II-38.3, CAS 1135205-94-5

Product Description: AWL-II-38.3 is a potent ephrin-A receptor (EphA3) kinase inhibitor. AWL-II-38.3 does not exhibit significant cellular activity against Src-family kinases nor against b-raf[1][2][1][2].

Applications: Cancer-Kinase/protease

Formula: C23H18F3N5O3

References: [1] Yongmun Choi, et al. Discovery and structural analysis of Eph receptor tyrosine kinase inhibitors. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4467-70./[2]Efrat Mashiach-Farkash, et al. Computer-based identification of a novel LIMK1/2 inhibitor that synergizes with salirasib to destabilize the actin cytoskeleton. Oncotarget. 2012 Jun;3(6):629-39.

CAS Number: 1135205-94-5

Molecular Weight: 469.42

Compound Purity: 99.71

Research Area: Cancer

Solubility: DMSO : 66.67 mg/mL (ultrasonic)

Target: Ephrin Receptor

• SKU: MEXHY-18832-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-18832-5
• Package Unit: 5 mg
• Quantity Unit: STK