AXC-715 (trihydrochloride), CAS 2479276-17-8

Product Description: AXC-715 (T785) trihydrochloride is a TLR7/TLR8 dual agonist, extracted from patent WO2020168017 A1[1]. AXC-715 trihydrochloride, compound D from WO2020190734A1, can be used for synthesis of antibody-adjuvant immunoconjugates, comprising an antibody construct that binds programmed death-ligand 1 (PD-L1) linked to one or more adjuvants[2].

Applications: COVID-19-immunoregulation

Formula: C18H28Cl3N5

References: [1]Sung-Ju Moon, et al. Compositions containing, methods and uses of antibody-tlr agonist conjugates. Patent WO2020168017A1./[2]Shelley Erin ACKERMAN, et al. Immunoconjugates targeting pd-l1. Patent WO2020190734A1.

CAS Number: 2479276-17-8

Molecular Weight: 420.81

Compound Purity: 99.76

Research Area: Inflammation/Immunology

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: Toll-like Receptor (TLR)

• SKU: MEXHY-138139B-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-138139B-50
• Package Unit: 50 mg
• Quantity Unit: STK