Azide-PEG5-Tos, CAS 236754-49-7

Product Description: Azide-PEG5-Tos is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azide-PEG5-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Applications: Cancer-programmed cell death

Formula: C17H27N3O7S

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

CAS Number: 236754-49-7

Molecular Weight: 417.48

Compound Purity: 98.0

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker

• SKU: MEXHY-140352-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-140352-50
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK