Azido-PEG4-Val-Cit-PAB-MMAE, CAS 1869126-64-6

Product Description: Azido-PEG4-Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the cleavable linker Azido-PEG4-Val-Cit-PAB-OH[1]. Azido-PEG4-Val-Cit-PAB-MMAE is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Formula: C69H113N13O17

References: [1]Moreadith R, et, al. Polyoxazoline antibody drug conjugates. WO2016019340A1.

CAS Number: 1869126-64-6

Molecular Weight: 1396.71

Compound Purity: 99.36

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Drug-Linker Conjugates for ADC

• SKU: MEXHY-W190943-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W190943-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK