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Encompassing Amino Acids: 22-460
Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Description: Recombinant human BACE1 (beta-site amyloid precursor protein cleaving enzyme 1), encompassing amino acids 22-460. This construct contains a C-terminal His-tag (10xHis). The recombinant protein was affinity purified.
Format: Aqueous buffer solution
Formulation: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, 20% glycerol
Genbank: NM_012104
Host Cell Line: HEK293
Purity: ≥90%
Storage Stability: At least 6 months at -80°C. Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 µg/ml in PBS + glycerol and stored at -80°C.
Tags: C-terminal His-Tag
Uniprot: P56817
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1.Luo, Y., et al., Neuroscience. 2001 4; 231-232.2.Cai, H., et al., Neuroscience. 2001 4; 233-234.
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