BAMEA-O16B, CAS 2490668-30-7

Formulation: A solution in methyl acetate

Formal Name: bis(2-(dodecyldisulfaneyl)ethyl) 3,3'-((3-methyl-9-oxo-10-oxa-13,14-dithia-3,6-diazahexacosyl)azanediyl)dipropionate

Purity: ≥95%

Formula Markup: C56H111N3O6S6

Formula Weight: 1114,9

Shelf life (days): 730

CAS Number: 2490668-30-7

Notes: BAMEA-O16B is a disulfide bond-containing ionizable cationic lipid.{66251} It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of CRISPR complementary single-guide RNA (sgRNA) and Cas9 mRNA for genome editing in vitro and in vivo. LNPs containing BAMEA-O16B encapsulating Cas9 mRNA and sgRNAs targeting the gene encoding proprotein convertase subtilisin kexin type 9 (PCSK9) accumulate in the liver and decrease serum PCSK9 levels in mice.

• SKU: CAY37439-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 37439-10
• Package Unit: 10 mg
• Quantity Unit: STK
• Application: Reinstoffe