Products from BPS Bioscience require a minimum order value above 400€
Applications: Great for screening small molecular inhibitors for drug discovery and HTS applications.
Description: The BCL-2 TR-FRET Assay Kit is designed to measure the inhibition of BCL-2binding to its ligand in a homogeneous 384 reaction format. This FRET-based assay requires notime-consuming washing steps, making it especially suitable for high throughput screeningapplications. The assay procedure is straightforward and simple; a sample containing terbiumlabeleddonor, dye-labeled acceptor, BCL-2, peptide ligand, and an inhibitor is incubated for 120minutes. Then, the fluorescence intensity is measured using a fluorescence reader.
Storage Stability: At least 6 months from date of receipt when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: Filippakopoulos, P., et al.,Cell 2012; 149:214.
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