Clone Name: LN22
Application Note: IHC-P: 1:60. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 79
Form: Liquid
Buffer (with preservative): Tissue culture supernatant, 0.09% Sodium azide.
Concentration:
Background: The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
Uniprot ID: P41182
Antigen Species: Human
Immunogen: Prokaryotic recombinant protein corresponding to 1–350 amino acids of the N-terminus of the Bcl-6 human oncoprotein molecule.
Purification: Unpurified
Conjugation: Unconjugated
Full Name: BCL6 transcription repressor
English
Deutsch
