Clone Name: C-10
Light Chain: Kappa
Application Note: IHC-P: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 192
Positive Control: Endometrial stromal sarcoma
Form: Liquid
Buffer (with preservative): Tris-HCl buffer, 0.2% BSA, 0.09% Sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.[provided by RefSeq, Jun 2010]
Uniprot ID: Q6W2J9
Antigen Species: Human
Immunogen: A synthetic peptideagainst amino acid 1-300 mapping at the N-terminus of BCOR of human origin
Purification: Purified IgG
Conjugation: Unconjugated
Full Name: BCL6 corepressor