BI-3802, CAS 2166387-65-9

Product Description: BI-3802 is a highly potent BCL6 degrader and inhibits the Bric-à-brac (BTB) domain of BCL6 with an IC50 of ≤3 nM. BI-3802 induces the polymerization of BCL6 and promotes BCL6 degration depended on E3 ligase SIAH1. BI-3802 has antitumor activity[1][2].

Applications: Cancer-programmed cell death

Formula: C24H29ClN6O3

References: [1]Kerres N, et al. Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6. Cell Rep. 2017 Sep 19;20(12):2860-2875./[2]Mikołaj Słabicki, et al. Small-molecule-induced polymerization triggers degradation of BCL6. Nature. 2020 Nov 18.

CAS Number: 2166387-65-9

Molecular Weight: 484.98

Compound Purity: 99.43

Research Area: Cancer

Solubility: DMSO : 5 mg/mL (ultrasonic)

Target: Bcl-2 Family;Molecular Glues

• SKU: MEXHY-108705-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-108705-50
• Package Unit: 50 mg
• Quantity Unit: STK