Formulation: A solid
Formal Name: 7,7′-dimethoxy-[4,4′-bi-1,3-benzodioxole]-5,5′-dicarboxylic acid, 5,5′-dimethyl ester
Purity: ≥95%
Formula Markup: C20H18O10
Formula Weight: 418,4
Shelf life (days): 1460
CAS Number: 73536-69-3
Notes: Bifendate is a derivative of schisandrin C (Item No. 27475) that has been found in S. chinensis and has diverse biological activities.{51636,51637,51638} It reduces lysosomal function and prevents autophagosome-lysosome fusion induced by the mTOR inhibitor Torin 2 (Item No. 14185) in HeLa cells when used at concentrations of 10 and 50 µM.{51636} Bifendate (45 µM) reduces MDA-MB-231 breast cancer cell migration in a scratch assay.{51637} Intragastric administration of bifendate (0.03-1 g/kg) reduces hepatic total cholesterol and triglyceride levels in a mouse model of high-fat diet-induced hypercholesterolemia.{51638}
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