Scientific Background: A structurally novel activator of SIRT1 (EC150=1 µM). Displays selectivity over SIRT2 and 3 (EC150=25 and 50 µM respectively). Cell permeable.
References: 1. Mai A., et al. (2009) J. Med. Chem. 52: 5496.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.