BNC-105, CAS 945771-74-4

Formulation: A solid

Formal Name: (7-hydroxy-6-methoxy-2-methyl-3-benzofuranyl)(3,4,5-trimethoxyphenyl)-methanone

Purity: ≥98%

Formula Markup: C20H20O7

Formula Weight: 372,4

Shelf life (days): 1460

CAS Number: 945771-74-4

Notes: BNC-105 is an inhibitor of tubulin polymerization.{64693} It inhibits bovine tubulin polymerization in a cell-free assay (EC50 = 3 µM). BNC-105 inhibits the proliferation of human umbilical vein endothelial cells (HUVECs) and human abdominal aorta endothelial cells (HAAECs; EC50s = 0.31 and 0.1 nM, respectively). It inhibits the proliferation of MCF-7 breast cancer cells (IC50 = 2.4 nM), as well as a panel of 9 additional cancer cell lines (IC50s = 0.16-18.4 nM).{64692} BNC-105 (1 nM) inhibits HUVEC capillary tube formation in a Matrigel™ assay.{64693}

• SKU: CAY36930-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36930-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK
• Application: Reinstoffe