Clone Name: 24C5
Application Note: *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 15
Specificity/Sensitivity: Human BNP and proBNP.
Form: Liquid
Buffer (with preservative): PBS, 0.09% sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Nov 2014]
Uniprot ID: P16860
Antigen Species: Human
Immunogen: Synthetic human BNP peptide a.a.r. 11-22 conjugated with carrier protein.
Purification: Protein A purified
Conjugation: Unconjugated
Full Name: natriuretic peptide B